Small but Mighty
Miniature antibodies discovered in sharks and camels are a boon for research and perhaps medicine.
Science,
2018
References:
Hamers-Casterman et al. (1993)
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Recommendation
Camels, llamas and sharks make antibodies smaller than humans’. After being discovered in the late 1980s, they have proven quite useful in the lab. In living organisms, their small size enables these “nanobodies” to bind to molecules and get into cellular spaces that larger antibodies can’t. Mitch Leslie’s article in Science describes a llama antibody’s role in research that was awarded a Nobel Prize – and how nanobodies may help human patients. getAbstract recommends this article to anyone curious about how new technologies get harnessed by researchers and clinicians.
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About the Author
Mitch Leslie writes for Science magazine about cell biology and immunology.
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