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Time Trials
Article

Time Trials

Chronotherapy – the specific timing of drug delivery – has shown promise in clinical trials. But that may not be enough to overcome the practical challenges.

Nature, 2018


Editorial Rating

8

Qualities

  • Innovative
  • Scientific
  • Eye Opening

Recommendation

Doctors may prescribe drugs for specific times of the day to get better outcomes. Heartburn, high blood pressure and erectile dysfunction drugs work best when patients take them at certain times of day. Even surgeries and procedures can have peak performance times. Researchers are experimenting with time-of-day regimens from cancer trials to cardiac surgery. Scientists who discovered circadian rhythms and cell regulation won the Nobel Prize. Science writer Lynne Peeples explores the landscape of chronotherapy, which will enthrall those who herald the next wave of precision medicine.

Take-Aways

  • Chronotherapy or chronomedicine is the timing of drug delivery.
  • Scheduling surgery for specific times can improve outcomes and reduce risks.
  • Some drugs work best when taken at specific times of the day.

About the Author

Lynne Peeples is a science writer from Seattle, Washington.


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