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Finding a New Purpose for Old Drugs
Article

Finding a New Purpose for Old Drugs

Drugs used for the treatment of asthma might prevent Parkinson’s disease

Science, 2017

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Editorial Rating

7

Qualities

  • Scientific
  • Well Structured
  • For Experts

Recommendation

Recent scientific advances have allowed researchers to better define the mechanisms of action (MOA) underlying Parkinson’s disease (PD). Such developments in PD research serve to expand the fundamental knowledge of the disease, referred to as the “shaking palsy” back in 1817. The article explores some of the steps necessary to further optimize PD therapy and treatment as well as its relationship to asthma. getAbstract recommends this article to physicians and scientists concerned with the treatment of PD.

Take-Aways

  • Scientists know what causes Parkinson’s disease (PD) and research is shifting towards medication that targets its source. 
  • Asthma medication works by blocking β2-adrenoreceptors; adrenoreceptor agonists reduce the rate of developing PD. 
  • Blocking the β2-adrenoreceptors decreases the expression of the gene ultimately responsible for PD, but the mechanism of action (MOA) is not well defined.

About the Author

Evan Snyder is director of the Center for Stem Cells and Regenerative Medicine at Sanford Burnham Prebys Medical Discovery Institute in California. Snyder obtained his MD and PhD in neuroscience from the University of Pennsylvania.


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